| Date | Location | Result | |
| 02/19/22 | Danville, Va. (Grant Center) | Methodist 64, Averett 63 | Box score |
| 02/17/22 | Fayetteville, N.C. (Riddle Center) | Methodist 84, Pfeiffer 82 | Box score |
| 02/15/22 | Raleigh, N.C. (Hermann Student Center) | William Peace 76, Methodist 68 | Box score |
| 02/12/22 | Fayetteville, N.C. (Riddle Center) | Methodist 74, Mary Baldwin 69 | Box score |
| 02/10/22 | Fayetteville, N.C. (Riddle Center) | Southern Virginia 73, Methodist 62 | Box score |
| 02/07/22 | Misenheimer, N.C. (Merner Gymnasium) | Pfeiffer 85, Methodist 69 | Box score |
| 02/05/22 | Fayetteville, N.C. (Riddle Center) | Greensboro 72, Methodist 66 | Box score |
| 02/02/22 | Fayetteville, N.C. (Riddle Center) | NC Wesleyan College 77, Methodist 58 | Box score |
| 01/31/22 | Greensboro, N.C. (Hanes Gymnasium) | Greensboro 64, Methodist 55 | Box score |
| 01/29/22 | Mary Baldwin, Va. (PAC) | Mary Baldwin 81, Methodist 63 | Box score |
| 01/28/22 | Buena Vista, Va. (Knight Arena) | Southern Virginia 78, Methodist 65 | Box score |
| 01/25/22 | Rocky Mount, N.C. (Everett Gymnasium) | NC Wesleyan College 98, Methodist 87 | Box score |
| 01/23/22 | Fayetteville, N.C. (Riddle Center) | Averett 81, Methodist 56 | Box score |
| 12/13/21 | Fayetteville, N.C. (Riddle Center) | William Peace 69, Methodist 58 | Box score |
| 12/11/21 | Fayetteville, N.C. (F.J. Capel Arena) | Fayetteville State 71, Methodist 46 | Box score |
| 12/01/21 | Fayetteville, N.C. (Riddle Center) | Mary Washington 70, Methodist 63 | Box score |
| 11/28/21 | Fayetteville, N.C. (Riddle Center) | Ferrum 76, Methodist 72 | Box score |
| 11/23/21 | Charlotte, N.C. (The Wildcat Center) | Johnson & Wales (NC) 210, Methodist 71 | Box score |
| 11/20/21 | Fayetteville, N.C. | Piedmont 77, Methodist 75 | Box score |
| 11/17/21 | Salem, Va. | Roanoke 65, Methodist 63 | Box score |
| 11/14/21 | Fayetteville, N.C. | Lynchburg 83, Methodist 70 | Box score |
| 11/11/21 | Fayetteville, N.C. | Methodist 66, Guilford 64 | Box score |
| 11/06/21 | Virginia Beach, Va. | NC Wesleyan College 90, Methodist 59 | Box score |
| 11/05/21 | Virginia Beach, Va. | Wis.-La Crosse 73, Methodist 50 | Box score |